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| Treatment of dunning R3327 prostatic adenocarcinoma in rats by ablatherm (en Anglais) | |||
Droits : Droits réservés à l'éditeur et aux auteurs Auteur(s) : GELET Albert, MARGORANI J., CHAPELON J., CATHIGOL D., FILMED 01-01-1992 Description : The experimental Dunning R 3327 prostatic adenocarcinoma is developped in Fisher/Copenhague hybrid rats. The Mat-Ly Lu subline is the most agressive : approximately 20 days after subcutaneous inoculation, the animal presents a large tumor associated with multiple metastases which provoke death. The ablatherm is an extracorporal treatment device which generates high energy focused ultrasounds. It is made up of a shot device (which includes a 7,5 KW amplifier, a pulse generator, a frequency generator and a 1 MHz transducer), a localization device (which includes a strereotaxic arm and an ultrasound) and a computer for both shots and device movements control. The dunning tumors are irradited 5 to 7 days after inoculation. Focused ultrasound absobtion by the tumor leads to partial or total destruction of the tumor by a mechanism which associates hyperthermia and cavitation. In rats treated with success (total destruction to the tumour), we can see a progressive disappearance of the tumor with no local recurrence. Some animals develop distant metastases but others show a long term survival with to local recurrence. Some animals develop distant metastases but others show a long term survival with no detectable metastases. In certain conditions, the Ablatherm could destruct the Dunning R 3327 May-Ly Lu adenocarcinoma and il could also cure the animal whith no adjuvant therapy. FILMED_92_5204_469 1992 Mots-clés libres : ablatherm, Dunning R3327, FILMED, prostatic adenocarcinoma | TECHNIQUE Type : image en mouvement Format : video/x-flv Source(s) : rtmp://streamer2.cerimes.fr/vod/canalu/videos/cutms/92-5404-469 | ||
Entrepôt d'origine : Canal-U - OAI Archive Identifiant : oai:canal-u.fr:156443 Type de ressource : Ressource documentaire | |||
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| (en Anglais) | |||||||||
Identifiant de la fiche : 156443 Schéma de la métadonnée : LOMv1.0, LOMFRv1.0 Droits : libre de droits, gratuit Droits réservés à l'éditeur et aux auteurs Auteur(s) : GELET ALBERT, MARGORANI J., CHAPELON J., CATHIGOL D. Éditeur(s) : FILMED 01-01-1992, 01-01-1992, 01-01-1992, 01-01-1992 Mots-clés libres : ablatherm, Dunning R3327, filmed, prostatic adenocarcinoma
| PEDAGOGIQUE Type pédagogique : cours / présentation Niveau : enseignement supérieur, formation continue, autres TECHNIQUE Type de contenu : image en mouvement Format : video/x-flv Taille : 33.12 Mo Durée d'exécution : 9 minutes 52 secondes RELATIONS Cette ressource fait partie de : | ||||||||
Entrepôt d'origine : Canal-U - OAI Archive Identifiant : oai:canal-u.fr:156443 Type de ressource : Ressource pédagogique | |||||||||
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