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| Self and non-self in fungi (en Français,Anglais) | |||
Droits : Creative Commons (BY NC) Auteur(s) : SAUPE Sven, PAOLETTI Mathieu, VISENTIN Jonathan, Université de Bordeaux - Service Audiovisuel et Multimédia Éditeur(s) : Université de Bordeaux - Service Audiovisuel et Multimédia 12-01-2016 Description : >> Sven Saupe : Self, identity, fungi The notion of self is a rich but ambiguous concept that is used in a wide array of academic disciplines including immunology, psychology and philosophy (in particular in different branches of phenomenology). I would like to give an introduction to the application of this concept in the description of a cell-cell interaction phenomenon occurring in many if not all filamentous fungi and designated incompatibility. The term self non-self recognition is often used to classify this phenomenon thus stressing its likeness to other biological phenomena going under the same designation such as immune recognition or gamete recognition in plant allofertilization. After giving a direct description of incompatibility, I shall describe the molecular basis of a specific case of incompatibility mechanism involving a prion protein. Time permitting I would like to use the specific example of fungal incompatibility, to attempt to illustrate my impression of the role narration and symbolism (in the form of metaphors) play in the practice of research and textual rendition of scientific results. >> Mathieu Paoletti : Self and non-self in fungi Fungi are engaged in various biotic interactions requiring discrimination between self and nonhet loci defining incompatibility encode proteins displaying similarities with NOD Like Receptor (NLRs) of plant and animal innate immune systems. In the model species Podospora anserina genetic interactions between incompatible alleles of het-c and het-e mediate VI. het-e encodes a NLR protein while het-c codes for a glycolipid transfer protein. Evolutionary properties of these genes lead us to hypothesize that in addition to VI their products could function as fungal immune receptors following the guard model whereby HET-e recognizes alterations of HET-c as a consequence pathogen’s action. I will describe recently developed experimental models to assess HET-c and HET-e functions in detection of and response to hetero-specific non self. I will also briefly describe the huge repertoire of NLR encoded by fungal genomes that may be involved in non self recognition in different biotic interactions. >> Jonathan Visentin : Vegetative incompatibility in fungi looks like graft rejection in human Mots-clés libres : immunologie,histocompatibilité,champignons,soi et non soi,self and non self,fungi | TECHNIQUE Type : image en mouvement Format : video/x-flv Source(s) : rtmpt://fms2.cerimes.fr:80/vod/groupe_dcam/self.an.non.self.in.fungi_20131/philosophie.et.biologie_sven.saupe_mdeb.mp4 | ||
Entrepôt d'origine : Canal-u.fr Identifiant : oai:canal-u.fr:20131 Type de ressource : Ressource documentaire | |||
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| Self and non-self in fungi (en Français, Anglais) | |||||||||
Identifiant de la fiche : 20131 Schéma de la métadonnée : LOMv1.0, LOMFRv1.0 Droits : libre de droits, gratuit Droits réservés à l'éditeur et aux auteurs. Creative Commons (BY NC) Auteur(s) : SAUPE SVEN, PAOLETTI MATHIEU, VISENTIN JONATHAN Éditeur(s) : Université de Bordeaux - Service Audiovisuel et Multimédia, Université de Bordeaux - Service Audiovisuel et Multimédia, Université de Bordeaux - Service Audiovisuel et Multimédia 12-01-2016, 12-01-2016, 12-01-2016 Description : >> Sven Saupe : Self, identity, fungi The notion of self is a rich but ambiguous concept that is used in a wide array of academic disciplines including immunology, psychology and philosophy (in particular in different branches of phenomenology). I would like to give an introduction to the application of this concept in the description of a cell-cell interaction phenomenon occurring in many if not all filamentous fungi and designated incompatibility. The term self non-self recognition is often used to classify this phenomenon thus stressing its likeness to other biological phenomena going under the same designation such as immune recognition or gamete recognition in plant allofertilization. After giving a direct description of incompatibility, I shall describe the molecular basis of a specific case of incompatibility mechanism involving a prion protein. Time permitting I would like to use the specific example of fungal incompatibility, to attempt to illustrate my impression of the role narration and symbolism (in the form of metaphors) play in the practice of research and textual rendition of scientific results. >> Mathieu Paoletti : Self and non-self in fungi Fungi are engaged in various biotic interactions requiring discrimination between self and nonhet loci defining incompatibility encode proteins displaying similarities with NOD Like Receptor (NLRs) of plant and animal innate immune systems. In the model species Podospora anserina genetic interactions between incompatible alleles of het-c and het-e mediate VI. het-e encodes a NLR protein while het-c codes for a glycolipid transfer protein. Evolutionary properties of these genes lead us to hypothesize that in addition to VI their products could function as fungal immune receptors following the guard model whereby HET-e recognizes alterations of HET-c as a consequence pathogen’s action. I will describe recently developed experimental models to assess HET-c and HET-e functions in detection of and response to hetero-specific non self. I will also briefly describe the huge repertoire of NLR encoded by fungal genomes that may be involved in non self recognition in different biotic interactions. >> Jonathan Visentin : Vegetative incompatibility in fungi looks like graft rejection in human Mots-clés libres : immunologie, histocompatibilité, champignons, soi et non soi, self and non self, fungi
| PEDAGOGIQUE Type pédagogique : cours / présentation Niveau : enseignement supérieur TECHNIQUE Type de contenu : image en mouvement Format : video/x-flv Taille : 453.19 Mo Durée d'exécution : 1 heure 16 minutes 45 secondes RELATIONS Cette ressource fait partie de : | ||||||||
Entrepôt d'origine : Canal-u.fr Identifiant : oai:canal-u.fr:20131 Type de ressource : Ressource pédagogique | |||||||||
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